It works to enhance serotonin and norepinephrine transmission and it functions as micro opioid receptor activation agent. The nerves carry messages from the limbs to the brain. If any particular part of the body experiences pain then the signaling speed increases and this translates to a pain signal in the brain. Tramadol decreases the transmission of signals from nerve ends by working on opioid receptors in the brain. It also increases dopamine turnover on the mu-opioid receptors resulting in a milder action than pure morphine or other opiates. Tramadol is metabolized into O-desmethyltramadol which results in the inhibition of uptake of norepinephrine. The mu-opioid receptors and the norepinephrine and serotonin functions of tramadol result in the analgesic effect. By affecting serotonin levels and increasing them, tramadol serves as a mood enhancer and reduces depression.
Understanding how tramadol functions in two ways on the brain and therefore the sensory system leads us to understand why it is as successful as a pain killer in people suffering moderate to severe pain. Understanding that it alters serotonin levels and also acts on the dopamine levels (both are “feel good” chemicals in the brain) can explain why it is favored so much by a large number of people as a recreational “mood elevating” drug.
Those who are out to get high focus on the easy availability of tramadol online and that popping a half dozen pills will keep them feeling high for 4 to 6 hours. The effect plateaus off but by popping a few more they manage to float on pink clouds. Users describe the state as a feeling of pleasurable high washing over them in waves while they feel clear headed. The buzz is euphoric.
Tramadol is made for a specific purpose: to alleviate pain. Like any other drug of the opiate class, it is abused. Like other opiates it becomes addictive since the brain becomes habituated and craves the euphoria. Because it affects serotonin and also dopamine, withdrawal symptoms can exhibit themselves and make it difficult for a user to give up its use. However, even before they get to that stage there are issues arising out of excess use and wrong way of using the drug like snorting or injecting it. Mixed with alcohol or other medication it can cause nasty side effects. The effects are dizziness, drowsiness and impaired coordination. Excess can lead to kidney and liver failure as well as convulsions. It gives a temporary mental lift but it can drop you into a bottomless pit on prolonged and excess use.
The genuine application of tramadol is for treating chronic and acute pain and tramadol can be bought online for such purposes. The maximum dose is 400 mg spread over 2 to 4 doses in a day and this keeps at bay unbearable or irritating pain. If you use it as a pleasure drug, you will find that you have to consume a far higher amount and, at the end of the day, it is not worth the temporary euphoria.
2 Yaers Ago, Saturday, June 25, 2016, 04:08:55